生殖補助医療に貢献する目的で、下記のような技術の開発を目指しています。
・体外受精および胚発生の成績向上につながる技術
・顕微授精などのマニピュレーションを用いて配偶子（卵子や精子）や胚を操作する技術
・未成熟生殖細胞の体外成熟培養などの技術
・生殖細胞の凍結保存技術

【アガロースカプセル関連】
(1)H. Nagatomo, T. Yao, Y. Araki, E. Mizutani, T. Wakayama, Agarose capsules as new tools for protecting denuded mouse oocytes/embryos during handling and freezing-thawing and supporting embryonic development in vivo., Sci. Rep., vol. 7, (1), 17960, Dec. 2017.
(2)S. Hatakeyama, S. Tokuoka, H. Abe, Y. Araki, Y. Araki, Cryopreservation of very low numbers of spermatozoa from male patients undergoing infertility treatment using agarose capsules., Hum. Cell, vol. 30, (3), 201–208, Jul. 2017.
(3)Y. Araki, T. Yao, Y. Asayama, A. Matsuhisa, Y. Araki, A single human sperm cryopreservation method using hollow-core agarose capsules., Fertil. Steril., vol. 104, (4), 1004–1009, Jul. 2015.

【精子細胞培養関連】
(1)A. Gohbara, K. Katagiri, T. Sato, Y. Kubota, H. Kagechika, Y. Araki, Y. Araki, T. Ogawa, In vitro murine spermatogenesis in an organ culture system., Biol. Reprod., vol. 83, 261–267, 2010.
(2)Y. Araki, T. Sato, K. Katagiri, Y. Kubota, T. Ogawa, Proliferation of mouse spermatogonial stem cells in microdrop culture., Biol. Reprod., vol. 83, 951–957, 2010.

【染色体解析関連】
(1)Y. Araki, M. Yoshizawa, Y. Araki, Visualization of human sperm chromosomes by using mouse oocytes cryothawed after enucleation., Fertil. Steril., vol. 86, 348–351, 2006.
(2)Y. Araki, M. Yoshizawa, Y. Araki, A novel method for chromosome analysis of human sperm using enucleated mouse oocytes., Hum. Reprod., vol. 20, 1244–1247, 2005.
(3)Y. Araki, M. Yoshizawa, H. Abe, Y. Murase, Y. Araki, Use of mouse oocytes to evaluate the ability of human sperm to activate oocytes after failure of activation by intracytoplasmic sperm injection., Zygote., vol. 12, 111–116, 2004.

【受精障害関連】
(1)H. Kamiyama, T. Shimizu, T. Oki, T. Asada, Y. Araki, Y. Araki, H. Kamiyama, T. Shimizu, T. Oki, T. Asada, Y. Y. Araki, Successful delivery following intracytoplasmic sperm injection with calcium ionophore A23187 oocyte activation in a partially globozoospermic patient, Reprod. Med. Biol., vol. 11, (3), 159–164, Mar. 2012.
(2)Y. Murase, Y. Araki, S. Mizuno, C. Kawaguchi, M. Naito, M. Yoshizawa, Y. Araki, Pregnancy following chemical activation of oocytes in a couple with repeated failure of fertilization using ICSI: case report., Hum. Reprod., vol. 19, 1604–1607, 2004.

【未成熟卵の体外成熟培養関連】
(1)堀川隆, 猪野友香里, 荒木泰行, 藤村佳子, 大場奈穂子, 神沢典子, 椛嶋香央里, 中楯真朗, 久保祐子, 佐藤雄一, 低刺激周期で得られたヒト卵胞液を用いたマウス未熟卵の体外成熟培養, J. Mamm. Ova Res., vol. 2, (1), 1–7, 2017.

【カフェイン関連】
(1)Y. Yokota, H. Yokota, M. Yokota, Y. Araki, Y. Araki, In vitro fertilization embryo development from caffeine-treated murine sperm, Reprod. Med. Biol., vol. 14, (3), 117–121, 2015.
(2)H. Yokota, Y. Yokota, M. Yokota, Y. Araki, Y. Araki, Effect of long-term caffeine administration to mice on in vitro fertilization and embryo development using oocytes, Reprod. Med. Biol., vol. 12, (4), 167–171, 2013.

【アシストハッチング関連】
(1)政井哲兵, 堀川隆, 大谷香央里, 松岡典子, 猪野友香里, 小林はつ美, 天田千尋, 大場奈穂子, 藤村佳子, 荒木泰行, 佐藤雄一, 凍結融解胚盤胞移植におけるレーザーアシステッドハッチングの有効性についての検討, 日本受精着床学会雑誌, vol. 30, (1), 17–19, 2013.
(2)畠山将太, 小野原千恵, 徳岡晋, 荒木泰行, 荒木康久, Assisted hatchingされた凍結・融解胚盤胞の移植時状態（脱出完了、脱出中、未脱出）と妊娠率の関係., 日本受精着床学会雑誌., vol. 28, 85–89, 2011.